A number of experiences have demonstrated how digital solutions are effective in improving quality of life (QoL) and health outcomes for older adults. Smart Health Age-Friendly Environments (SHAFE) is a new concept introduced in Europe since 2017 that combines the concept of Age-Friendly Environments with Information Technologies, supported by health and community care to improve the health and disease management of older adults and during the life-course. This chapter aims to provide an initial overview of the experiences available not only (...) in Europe, based on the research work of the participants of the International Interdisciplinary Network on Health and Well-being in an Age-Friendly Digital World (NET4Age-Friendly), which could be of interest to preventive, health and social authorities. The chapter reports good practices, pain points, and bottlenecks that may require a collaborative, interdisciplinary research approach to facilitate the transformations towards smart, sustainable, health and age-friendly cities and communities. (shrink)

Philosophers have debated at length the epistemological status of scientific thought experiments. I contend that the literature on this topic still lacks a common conceptual framework, a lacuna that produces radical disagreement among the participants in this debate. To remedy this problem, I suggest focusing on the distinction between the internal and the external validity of an experiment, which is also crucial for thought experiments. I then develop an account of both kinds of validity in the context of thought experiments. (...) I show that we can naturally conceptualise internal validity in terms of games of make-believe. Then, I argue that external validity is best defined as accurate representation of a target system. Finally, I turn back to the current debate on thought experiments and show that my diarchic account provides a general framework that can be shared by the competing philosophical views, as well as a fruitful guide for their reconciliation. (shrink)

This paper attempts a reconstruction of reason’s contribution to empirical truth in connection with Kant’s definition of truth as the agreement of cognition with its object. I argue that Kant’s treatment of truth in the Transcendental Analytic gets completed in the Appendix to the Transcendental Dialectic with an often neglected but compelling argument (what I shall call the Variety Argument). This argument postulates such a variety in the appearances as to undermine any attempt at formulating empirical truths. Crucially, I argue (...) that this variety does not depict an extreme-case scenario, but our own epistemic situation without reason. Reason completes Kant’s theory of truth by allowing the understanding (i.) to form empirical concepts and (ii.) approximate to empirical truth. (shrink)

Despite numerous and increasing attempts to define what life is, there is no consensus on necessary and sufficient conditions for life. Accordingly, some scholars have questioned the value of definitions of life and encouraged scientists and philosophers alike to discard the project. As an alternative to this pessimistic conclusion, we argue that critically rethinking the nature and uses of definitions can provide new insights into the epistemic roles of definitions of life for different research practices. This paper examines the possible (...) contributions of definitions of life in scientific domains where such definitions are used most (e.g., Synthetic Biology, Origins of Life, Alife, and Astrobiology). Rather than as classificatory tools for demarcation of natural kinds, we highlight the pragmatic utility of what we call operational definitions that serve as theoretical and epistemic tools in scientific practice. In particular, we examine contexts where definitions integrate criteria for life into theoretical models that involve or enable observable operations. We show how these definitions of life play important roles in influencing research agendas and evaluating results, and we argue that to discard the project of defining life is neither sufficiently motivated, nor possible without dismissing important theoretical and practical research. (shrink)

Theoretical accounts of development exhibit several internal tensions and face multiple challenges. They span from the problem of the identification of the temporal boundaries of development (beginning and end) to the characterization of the distinctive type of change involved compared to other biological processes. They include questions such as the role to ascribe to the environment or what types of biological systems can undergo development and whether they should include colonies or even ecosystems. In this chapter we discuss these conceptual (...) issues, and we argue that adopting an organizational approach may help solve or clarify them. -/- While development is usually identified with the achievement of an adult form with the capability to reproduce and therefore maintain a lineage, adopting the organizational approach may provide a different strategy, which focuses also on the maintenance of the current organization of the organism. By doing so an organizational approach favors a switch in perspective which consists in analyzing how organisms maintain their viability at each moment of development rather than considering them as going through intermediate stages of a process directed toward a specific goal state. This developmental dimension of biological organization has yet to be given a general and detailed analysis within the organizational theoretical perspective, apart from some preliminary attempts. How a biological organization is maintained through a series of radical organizational changes and what these changes are issues that still require clarification. In this chapter we offer the beginnings of such an analysis of developmental transitions, understood as changes in functionality brought forth by regulatory mechanisms in the context of the continued maintenance of organizational viability at every step. (shrink)

In the Critique of Pure Reason, Kant often remarks that phenomena consist only in relations. This is a highly puzzling thesis that is not easily reconcilable with the explanation of natural processes. More specifically, it is not clear whether and how a network of mere relations (such as ‘being higher than’, ‘being next to’, etc.) can give rise to genuine changes in nature. I call this the problem of global relationality. In this paper, I suggest a solution to this problem (...) by showing that Kant’s specific sense of relationality is ultimately grounded in the spatiality of phenomena and differs from the one usually assumed in the contemporary debate. I argue that a subset of empirical properties can be regarded as ‘comparatively intrinsic’ since they preserve a genuine sense of intrinsicness while being fully relational in space. As a result, real changes can take place in the phenomenal realm if they concern comparatively intrinsic properties of empirical objects. (shrink)

In this paper, I offer a systematic account of Kant’s view on ‘phenomenal substance’. Several studies have recently analyzed Kant’s notion of substance. However, I submit that more needs to be said about how this notion is reconceptualized within the critical framework to vindicate a genuine and legitimate sense of substance in the phenomenal realm. More specifically, I show that Kant’s transcendental idealism does not commit him to a rejection of substantiality in phenomena. Rather, Kant isolates a general notion of (...) substance (as ultimate subject) and argues that (i) the relationality of phenomena is compatible with this notion; and that (ii) matter and all its parts are the ultimate subjects of everything existing in space (as what is independently movable in space). I suggest that vindicating a genuine and legitimate notion of phenomenal substance has far-ranging consequences for the interpretation of Kant’s empirical realism. (shrink)

Spontaneous collapse theories of quantum mechanics turn the usual Schrödinger equation into a stochastic dynamical law. In particular, in this paper, I will focus on the GRW theory. Two philosophical issues that can be raised about GRW concern (i) the ontology of the theory, in particular the nature of the wave function and its role within the theory, and (ii) the interpretation of the objective probabilities involved in the dynamics of the theory. During the last years, it has been claimed (...) that we can take advantage of dispositional properties in order to develop an ontology for GRW theory, and also in order to ground the objective probabilities which are postulated by it. However, in this paper, I will argue that the dispositional interpretations which have been discussed in the literature so far are either flawed or – at best – incomplete. If we want to endorse a dispositional interpretation of GRW theory we thus need an extended account that specifies the precise nature of those properties and which makes also clear how they can correctly ground all the probabilities postulated by the theory. Thus, after having introduced several different kinds of probabilistic dispositions, I will try to fill the gap in the literature by proposing a novel and complete dispositional account of GRW, based on what I call spontaneous weighted multi-track propensities. I claim that such an account can satisfy both of our desiderata. (shrink)

We present an elementary system of axioms for the geometry of Minkowski spacetime. It strikes a balance between a simple and streamlined set of axioms and the attempt to give a direct formalization in first-order logic of the standard account of Minkowski spacetime in [Maudlin 2012] and [Malament, unpublished]. It is intended for future use in the formalization of physical theories in Minkowski spacetime. The choice of primitives is in the spirit of [Tarski 1959]: a predicate of betwenness and a (...) four place predicate to compare the square of the relativistic intervals. Minkowski spacetime is described as a four dimensional ‘vector space’ that can be decomposed everywhere into a spacelike hyperplane - which obeys the Euclidean axioms in [Tarski and Givant, 1999] - and an orthogonal timelike line. The length of other ‘vectors’ are calculated according to Pythagora’s theorem. We conclude with a Representation Theorem relating models of our system that satisfy second order continuity to the mathematical structure called ‘Minkowski spacetime’ in physics textbooks. (shrink)

Organization figures centrally in the understanding of biological systems advanced by both new mechanists and proponents of the autonomy framework. The new mechanists focus on how components of mechanisms are organized to produce a phenomenon and emphasize productive continuity between these components. The autonomy framework focuses on how the components of a biological system are organized in such a way that they contribute to the maintenance of the organisms that produce them. In this paper we analyze and compare these two (...) accounts of organization and argue that understanding biological organisms as cohesively integrated systems benefits from insights from both. To bring together the two accounts, we focus on the notions of control and regulation as bridge concepts. We start from a characterization of biological mechanisms in terms of constraints and focus on a specific type of mechanism, control mechanisms, that operate on other mechanisms on the basis of measurements of variables in the system and its environment. Control mechanisms are characterized by their own set of constraints that enable them to sense conditions, convey signals, and effect changes on constraints in the controlled mechanism. They thereby allow living organisms to adapt to internal and external variations and to coordinate their parts in such a manner as to maintain viability. Because living organisms contain a vast number of control mechanisms, a central challenge is to understand how they are themselves organized. With the support of examples from both unicellular and multicellular systems we argue that control mechanisms are organized heterarchically, and we discuss how this type of control architecture can, without invoking top-down and centralized forms of organizations, succeed in coordinating internal activities of organisms. (shrink)

Despite recent essentialist approaches to Kant’s laws of nature, it is unclear whether Kant’s critical philosophy is compatible with core tenets of essentialism. In this paper, I first reconstruct Kant’s position by identifying the key metaphysical and epistemological features of his notion of ‘nature’ or ‘essence’. Two theses about natures can be found in the literature, namely that they are noumenal in character (noumenal thesis) and that they guide scientific investigation as regulative ideas of reason (regulative thesis). I argue that (...) Kant’s notion of nature does not entail the noumenal thesis and, based on his model of causal explanation, I propose a novel, phenomenal thesis, that allows for a better understanding of the function of natures as regulative ideas. In the last part of the paper, I show that Kant’s ‘essentialism’ is a genuine form of essentialism committed to de re modality, although it differs in several respects from major contemporary essentialist accounts. I conclude by suggesting that Kant’s essentialism (if appropriately updated) can be relevant to the contemporary debate, which has so far been dominated by Humean and Aristotelian proposals. (shrink)

I consider a problem for functional reductionism, based on the following tension. Say that b is functionally reduced to a. On the one hand, a and b turn out to be identical, and identity is a symmetric relation. On the other hand, functional reductionism implies that a and b are asymmetrically related: if b is functionally reduced to a, then a is not functionally reduced to b. Thus, we ask: how can a and b be asymmetrically related if they are (...) the same thing? I propose a solution to this tension, by distinguishing between ontological levels and levels of description. (shrink)

Living organisms act as integrated wholes to maintain themselves. Individual actions can each be explained by characterizing the mechanisms that perform the activity. But these alone do not explain how various activities are coordinated and performed versatilely. We argue that this depends on a specific type of mechanism, a control mechanism. We develop an account of control by examining several extensively studied control mechanisms operative in the bacterium E. coli. On our analysis, what distinguishes a control mechanism from other mechanisms (...) is that it relies on measuring one or more variables, which results in setting constraints in the control mechanism that determine its action on flexible constraints in other mechanisms. In the most basic arrangement, the measurement process directly determines the action of the control mechanism, but in more complex arrangements signals mediate between measurements and effectors. This opens the possibility of multiple responses to the same measurement and responses based on multiple measurements. It also allows crosstalk, resulting in networks of control mechanisms. Such networks integrate the behaviors of the organism but also present a challenge in tailoring responses to particular measurements. We discuss how integrated activity can still result in differential, versatile, responses. (shrink)

The new mechanists and the autonomy approach both aim to account for how biological phenomena are explained. One identifies appeals to how components of a mechanism are organized so that their activities produce a phenomenon. The other directs attention towards the whole organism and focuses on how it achieves self-maintenance. This paper discusses challenges each confronts and how each could benefit from collaboration with the other: the new mechanistic framework can gain by taking into account what happens outside individual mechanisms, (...) while the autonomy approach can ground itself in biological research into how the actual components constituting an autonomous system interact and contribute in different ways to realize and maintain the system. To press the case that these two traditions should be constructively integrated we describe how three recent developments in the autonomy tradition together provide a bridge between the two traditions: (1) a framework of work and constraints, (2) a conception of function grounded in the organization of an autonomous system, and (3) a focus on control. (shrink)

The article examines education in the information age, proposing an informational perspective. By analyzing the epistemology of informational learning, I offer a framework for understanding how individuals acquire knowledge, highlighting the role of design and models in active and constructive learning. Following this, the paper presents the UDL and ODDE educational models, outlining their key features and potential contributions. I then showcase the practical application of these models through case studies focusing on the use of AI to develop personalized learning (...) tools and inclusive environments. I propose EIML as a competence to address the abundance of information in learning and the need for the concept of reciprocity. (shrink)

In this paper, we embark on the complicated discussion about the nature of vice in Virtue Ethics through a twofold approach: first, by taking seriously the claim that virtues (and certain flavours of vices) are genuinely dispositional features possessed by agents, and secondly, by employing a pluralistic attitude borrowed from Battaly’s pluralism (2008). Through these lenses, we identify three varieties of viciousness: incontinence, indifference, and malevolence. The upshot is that the notion of vice is not as categorically homogeneous as that (...) of virtue: some states of viciousness consist in interference of present virtuous dispositions, or mimicking of absent vicious ones, whereas others can be considered genuine dispositions themselves. Furthermore, this set-up can provide an interesting, albeit highly idealized story as to how, through the interference in one’s environment, one gets acquainted with vice in various degrees. Finally, this approach can be illuminating vis-à-vis Virtue Ethics in general; e.g. we can employ it to discuss more productively Johnston’s (2003) objection to Hursthouse’s (1999) account of moral conduct. Finally, this approach can be illuminating vis-a-vis Virtue Ethics in general; e.g. we can employ it to discuss more productively Johnston’s (2003) objection to Hursthouse’s (1999) account of moral conduct. (shrink)

There are various forms of teleological thinking central to debates in the early modern and modern periods, debates in which David Hume (1711–1776) is a key figure. In the first section, we shall introduce three levels at which teleological considerations have been incorporated into philosophical accounts of man and nature, and sketch Hume’s criticisms of these approaches. In the second section, we turn to Hume’s non-teleological ‘science of man’. In the third section, we show how Hume has an account of (...) human flourishing that is not dependent on teleology. In the fourth section, we shall speculate as to the relation between Hume’s account of human nature and contemporary evolutionary accounts of morality and reasoning. (shrink)

Endocrinologists apply the idea of feedback loops to explain how hormones regulate certain bodily functions such as glucose metabolism. In particular, feedback loops focus on the maintenance of the plasma concentrations of glucose within a narrow range. Here, we put forward a different, organicist perspective on the endocrine regulation of glycaemia, by relying on the pivotal concept of closure of constraints. From this perspective, biological systems are understood as organized ones, which means that they are constituted of a set of (...) mutually dependent functional structures acting as constraints, whose maintenance depends on their reciprocal interactions. Closure refers specifically to the mutual dependence among functional constraints in an organism. We show that, when compared to feedback loops, organizational closure can generate much richer descriptions of the processes and constraints at play in the metabolism and regulation of glycaemia, by making explicit the different hierarchical orders involved. We expect that the proposed theoretical framework will open the way to the construction of original mathematical models, which would provide a better understanding of endocrine regulation from an organicist perspective. (shrink)

In this article we analyse the problem of emergence in its diachronic dimension. In other words, we intend to deal with the generation of novelties in natural processes. Our approach aims at integrating some insights coming from Whitehead’s Philosophy of the Process with the epistemological framework developed by the “autopoietic” tradition. Our thesis is that the emergence of new entities and rules of interaction (new “fields of relatedness”) requires the development of discontinuous models of change. From this standpoint natural evolution (...) can be conceived as a succession of emergences — each one realizing a novel “extended” present, described by distinct models — rather than as a single and continuous dynamics. This theoretical and epistemological framework is particularly suitable to the investigation of the origin of life, an emblematic example of this kind of processes. (shrink)

According to the most common interpretation of the simulation argument, we are very likely to live in an ancestor simulation. It is interesting to ask if some families of simulations are more likely than others inside the space of all simulations. We argue that a natural probability measure is given by computational complexity: easier simulations are more likely to be run. Remarkably this allows us to extract experimental predictions from the fact that we live in a simulation. For instance we (...) show that it is very likely that humanity will not achieve interstellar travel and that humanity will not meet other intelligent species in the universe, in turn explaining the Fermi's Paradox. On the opposite side, experimental falsification of any of these predictions would constitute evidence against our reality being a simulation. (shrink)

Functionalism is the view that being x is to play the role of x. This paper defends a functionalist account of three-dimensional entities in the context of Wave Function Realism (WFR), that can explain in detail how we can recover three-dimensional entities out of the wavefunction. In particular, the essay advocates for a novel version of WFR in terms of a functional reductionist approach in the style of David Lewis. This account entails reduction of the upper entities to the bottom (...) ones, when the latter behave appropriately. As applied to WFR, it shows how the wavefunction can turn out to be identical to three-dimensional objects, provided certain conditions. The first major goal of the paper is thus to put forward an improved and more rigorous version of WFR, which dissolves several extant issues about the theory, and can serve as a starting point for future literature on the topic. Moreover, the second major goal of the article is to take WFR as a case study to demonstrate the pros of functional reductionism, especially in the form defended here, thereby helping to bring this view back in the philosophy of science debate. The positive upshots of this paper suggest a possible application of functional reductionism also to other contexts. (shrink)

The aim of this essay is to examine the path of the philosopher of religion Italo Mancini related to his early speculative period on meontology and to show a theoretical consonance with his later period of “double thoughts”. The first part of the contribution argues: it is possible to explain the meontological path as prolegomena to the non-being of being through an in-depth analysis of the notions in his youthful essay “e La struttura dell’essere" e "Il trascendentale come fondamento”, understood (...) as status quaestionis on ontology in general (§1, §2); it presents also why for Mancini transcendence and functionality ground his scheme of possibilities (§3, §4); we define why the fundamental reason why Mancini’s strategy works is entirely based on a theology of oxymorons: starting with double thoughts (§5), as an open and structured path, insofar as thought and revelation appear as a hermeneutic circle (§6); in the last part, we delve into the logic of fragmentariness as an integral principle of religious hermeneutics and, finally, a summary relation between Mancini’s first speculation and the last of his posthumous work “Frammento su Dio” is assessed (§7). (shrink)

In the Ethics, Spinoza famously rejects freedom of the will. He also offers an error theory for why many believe, falsely, that the will is free. Standard accounts of his arguments for these claims focus on their efficacy against incompatibilist views of free will. For Spinoza, the will cannot be free since it is determined by an infinite chain of external causes. And the pervasive belief in free will arises from a structural limitation of our self-knowledge: because we are aware (...) of our actions but unaware of their causes, we suppose that we alone must be responsible for them. Yet I argue that the standard accounts miss a further element of Spinoza’s arguments that also targets compatibilist views on which free will is consistent with a specific kind of determination—namely, self-determination in accordance with our value judgments. For Spinoza, we are misled not only in supposing that our actions lack external determination but also in thinking that they are determined by our representations of value. In fact, our actions are determined by our appetites, which are blind to our value judgments. And the pervasive belief that our actions are determined by such judgments arises from the projection of value onto the objects we seek. As he denies us free will, then, Spinoza also denies us a capacity central to agency—the capacity to determine our actions in accordance with our ideas of the good. This makes his arguments against free will more consequential, and more radical, than commonly assumed. (shrink)

The aim of this paper is to present some system-theoretical notions ─ such as constraint, closure, integration, coordination, etc. ─ which have recently raised a renovated interest and have undergone a deep development, especially in those branches of philosophy of biology characterized by a systemic approach. The im- plications of these notions for the analysis and characterization of self-maintaining organizations will be discussed with the aid of examples taken from models of minimal living systems, and some conceptual distinctions will be (...) provided. In the last part of the paper the epistemic implications of these ideas will be presented. (shrink)

The aim of this paper is to provide a theoretical framework to understand how multicellular systems realize functionally integrated physiological entities by organizing their intercellular space. From a perspective centered on physiology and integration, biological systems are often characterized as organized in such a way that they realize metabolic self-production and self-maintenance. The existence and activity of their components rely on the network they realize and on the continuous management of the exchange of matter and energy with their environment. One (...) of the virtues of the organismic approach focused on organization is that it can provide an understanding of how biological systems are functionally integrated into coherent wholes. Organismic frameworks have been primarily developed by focusing on unicellular life. Multicellularity, however, presents additional challenges to our understanding of biological systems, related to how cells are capable to live together in higher-order entities, in such a way that some of their features and behaviors are constrained and controlled by the system they realize. Whereas most accounts of multicellularity focus on cell differentiation and increase in size as the main elements to understand biological systems at this level of organization, we argue that these factors are insufficient to provide an understanding of how cells are physically and functionally integrated in a coherent system. In this paper, we provide a new theoretical framework to understand multicellularity, capable to overcome these issues. Our thesis is that one of the fundamental theoretical principles to understand multicellularity, which is missing or underdeveloped in current accounts, is the functional organization of the intercellular space. In our view, the capability to be organized in space plays a central role in this context, as it enables (and allows to exploit all the implications of) cell differentiation and increase in size, and even specialized functions such as immunity. We argue that the extracellular matrix plays a crucial active role in this respect, as an evolutionary ancient and specific (non-cellular) control subsystem that contributes as a key actor to the functional specification of the multicellular space and to modulate cell fate and behavior. We also analyze how multicellular systems exert control upon internal movement and communication. Finally, we show how the organization of space is involved in some of the failures of multicellular organization, such as aging and cancer. (shrink)

Scientific models typically contain idealizations, or assumptions that are known not to be true. Philosophers have long questioned the nature of idealizations: Are they heuristic tools that will be abandoned? Or rather fictional representations of reality? And how can we reconcile them with realism about knowledge of nature? Immanuel Kant developed an account of scientific investigation that can inspire a new approach to the contemporary debate. Kant argued that scientific investigation is possible only if guided by ideal assumptions—what he calls (...) “regulative ideas”. These ideas are not true of objects of nature, and yet they are not heuristic tools or fictional represen- tations. They are necessary rules governing the construction and assessment of scientific explanations. In this paper, I suggest that some idealizations can be interpreted as having necessary regulative value and as being compatible with scientific realism. I first analyze the puzzle of the nature of idealization and present the main approaches to this topic in the literature. Second, I reconsider the puzzle vis-a-vis a restricted, Kantian definition of idealization and a novel characterization of the relation between idealization and truth. Finally, I discuss in detail an example of idealization (the Hardy-Weinberg equilibrium) along the suggested Kantian lines. (shrink)

This paper critically revises the organisational account of teleology, which argues that living systems are first and foremost oriented towards a goal: maintaining their own conditions of existence. It points out some limitations of this account, mainly in the capability to account for the richness and complexity of biological systems and their purposeful behaviours. It identifies the reason of these limitations in the theoretical grounding of this account, specifically in the too narrow notion of closure of constraints, focused on self-production. (...) It proposes to ground an organisational account of biological teleology in the capability of living system not just to produce and replace their parts, but to control their own internal dynamics and behaviours in such a way as to maintain themselves. This theoretical framework has two advantages. It better captures the distinctive features of biological organisations and consequently the richness and active nature of their purposeful behaviours. By doing so, it makes it possible to apply this framework beyond minimal theoretical models to real biological cases. (shrink)

This paper aims to show how Kant’s account of theoretical reason can inform the contemporary debate over unity and pluralism of science. Although the unity of science thesis has been severely criticized in recent decades, I argue that pluralism as the sole epistemic principle guiding science is both too strong and too weak a principle. It is too strong because it does not account for the process of theory unification in science. It is too weak because it does not answer (...) the question of how science ought to be done. I then look at a promising ‘perspectival’ (i.e., epistemically situated) approach to the problem Kant presents in the Appendix to the Transcendental Dialectic. I argue that the logical principles of systematicity (homogeneity, specification, continuity) form a ‘perspectival space’ within which scientists can pursue both unity and disunity of cognition. Finally, I suggest that the existing conflict between pluralism and unity ultimately resides in a metaphysical characterization of unity that does not correctly capture its epistemic significance in science. Looking at Kant’s ‘perspectivism’ not only allows us to resolve this apparent antinomy, but also to rethink unity and pluralism as mutually inclusive regulative principles. (shrink)

In his Bibliographia politica Naudé reviews in about one hundred pages authors and works that have dealt with politics, from the Antiquity to the first decades of the Seventeenth Century. In few enlightened pages on the ordinary and extraordinary administration of the State, Naudé elaborates his own idea of Reason of State, including the use of an extraordinary administration in the name of the public benefit. We can find a continuity between his Bibliographia politica and his Considérations politiques sur les (...) coups d’Estat. In both his political works Naudé gives to the category of wisdom, derived from Aristotle, a new practical and political value, which goes back to authors such as Machiavelli or Cardano, Lipsius or Charron. Naudé’s political wisdom uses dissimulation and any form of justice, also against common law, to act in extraordinary administration of the State or to carry out “coups d’État.”. (shrink)

It has been argued that Humean Supervenience is threatened by the existence of quantum entanglement relations. The most conservative strategy for defending HS is to add the problematic entanglement relations to the supervenience basis, alongside spatiotemporal relations. In this paper, I’m going to argue against this strategy by showing how certain particular cases of tripartite entanglement states – i.e. GHZ states – posit some crucial problems for this amended version of HS. Moreover, I will show that the principle of free (...) recombination – which is strictly linked to HS – is severely undermined if we add entanglement relations to the supervenience basis. I conclude that the conservative move is very unappealing, and therefore the defender of HS should pursue other, more controversial, strategies. (shrink)

Can an identity be the proper subject of an explanation? A popular stance, albeit not one often argued for, gives a negative answer to this question. Building from a contentious passage from Jaegwon Kim in this direction, we reconstruct an argument to the conclusion that identities, to the extent in which they are necessary, cannot be explained. The notion of contrastive explanation, characterized as difference-seeking, will be crucial for this argument; however, we will eventually find the argument to be unsatisfactory. (...) On the contrary, the discussion provides enough resource to sketch a very simple framework for a non-causal contrastive explanation of identities. Many instances will be provided, with different varieties of explanans, ultimately suggesting that certain entailment or biconditional principles involving identities (first and foremost, so-called two-level identity criteria) may indeed be taken to have an inherent explanatory value. (shrink)

This paper focuses on physiological integration in multicellular systems, a notion often associated with biological individuality, but which has not received enough attention and needs a thorough theoretical treatment. Broadly speaking, physiological integration consists in how different components come together into a cohesive unit in which they are dependent on one another for their existence and activity. This paper argues that physiological integration can be understood by considering how the components of a biological multicellular system are controlled and coordinated in (...) such a way that their activities can contribute to the maintenance of the system. The main implication of this perspective is that different ways of controlling their parts may give rise to multicellular organizations with different degrees of integration. After defining control, this paper analyses how control is realized in two examples of multicellular systems located at different ends of the spectrum of multicellularity: biofilms and animals. It focuses on differences in control ranges, and it argues that a high degree of integration implies control exerted at both medium and long ranges, and that insofar as biofilms lack long-range control (relative to their size) they can be considered as less integrated than other multicellular systems. It then discusses the implication of this account for the debate on physiological individuality and the idea that degrees of physiological integration imply degrees of individuality. (shrink)

Open peer commentary on the article “Circularity and the Micro-Macro-Difference” by Manfred Füllsack. Upshot: The target article defends the fundamental role of circularity for systems sciences and the necessity to develop a conceptual and methodological approach to it. The concept of circularity, however, is multifarious, and two of the main challenges in this respect are to provide distinctions between different forms of circularities and explore in detail the roles they play in organizations. This commentary provides some suggestions in this direction (...) with the aim to supplement the perspective presented in the target article with some insights from theoretical biology. (shrink)

This essay aims to appreciate the evolution of the problems regarding the ontological understanding of the photographic image and its derivative, the film, in the face of the sophistication of the apparatus of its production. The creative freedom in making images through optical machines is inversely proportional to their credibility as documents. Since its appearance in the human landscape, as a cultural object, the technology of recording images with lights has brought with it a complex of aporias about what would (...) the nature of the image produced by cameras be: a document or an artistic object, intentionally produced and with created meaning? Consequently: are they denotative or, necessarily, connotative? The development of automatic image capture in the 1980s represented the first update of the question. To what extent, and for how long, will it be possible to trust photography and film as documents through which man aims to access reality? The question now seems to be settled, definitively, in the face of the invention of artificial photography made by algorithms. (shrink)

Graham Priest's book In Contradiction is a bold defense of the existence of true contradictions. Although Priest's case is impressive, and many of his arguments are correct, his approach is not the only one allowing for true contradictions. As against Priest's, there is at least one contradictorialist approach which establishes a link between true contradictions and degrees of truth. All in all, such an alternative is more conservative, closer to mainstream analytical philosophy. The two approaches differ as regards the floodgate (...) problem. Priest espouses a confinement policy banning contradictions except in a few special domains, particularly those of pure semantics and set-theory , whereas the alternative approach admits two negations -- natural or weak negation and strong negation, the latter being classical; accordingly, the alternative approach prohibits any contradiction involving strong negation, thus providing a syntactic test of what contradictions have to be rejected. (shrink)

In this essay, I offer a vindication of pride. I start by presenting the Christian condemnation of pride as the cardinal sin. I subsequently examine Mandeville’s line of argument whereby pride is beneficial to society, although remaining a vice for the individual. Finally, I focus on, and endorse, the analysis of pride formulated by Hume, for whom pride qualifies instead as a virtue. This is because pride not only contributes to making society flourish but also stabilizes the virtuous agent by (...) creating a virtuous circle between our desire for self-appraisal and our aspiration to act morally. I conclude by underscoring the (virtuous) connection between pride and modesty, concomitantly arguing that humility should be discarded as vicious. (shrink)

In this paper, I examine Eugenio Lecaldano’s way of tackling the issue of the meaning of life. I highlight the dependence of his individualistic approach on the specific character of the person who inquires into the meaning of life. I also sketch a weaker way of understanding the meaning of life as an attempt to provide reasons which are valid from the standpoint of the present, and which will make us continue living.

Definition The authors’ definition of the autopoietic system has evolved through the years. One of them states that an autopoietic system is organized (defined as a unity) as a network of processes of production (transformation and destruction) of components that produces the components which: (1) through their interactions and transformations regenerate and realize the network of processes (relations) that produced them; and (2) constitute it (the machine) as a concrete unity in the space in which they exist by specifying the (...) topological domain of its realization as such a network (Varela 1979, p. 13). Nearly the same formula was earlier used to define an autopoietic machine (Maturana and Varela 1973/1980, 1984/1987, p. 135). (shrink)

Since Saul Kripke’s influential work in the 1970s, the revisionary approach to semantic paradox—the idea that semantic paradoxes must be solved by weakening classical logic—has been increasingly popular. In this paper, we present a new revenge argument to the effect that the main revisionary approaches breed new paradoxes that they are unable to block.

In Pensare l’infosfera La filosofia come design concettuale, Luciano Floridi states the value of a correct analysis and philosophical responses within the information age we are living in. The aim of this paper is to suggest several ideas for reflecting on some of Floridi’s topics such as the analysis of presence, relationship and semantization. In the second paragraph, after a brief introduction about the author, I will analyse philosophical insights on the relationship between being and determination. In the third paragraph, (...) I am going to suggest the importance of a correct analysis of presence. In the fourth paragraph, a possible analogy between the philosophy of information and a certain form of neo-idealism will be shown. At last, I try to show how the philosophy of information can play a key role in the way we think about reality, but also its possible conceptual risks. (shrink)

The aim of this article is to investigate the relevance and implications of synthetic models for the study of the interactive dimension of minimal life and cognition, by taking into consideration how the use of artificial systems may contribute to an understanding of the way in which interactions may affect or even contribute to shape biological identities. To do so, this article analyzes experimental work in synthetic biology on different types of interactions between artificial and natural systems, more specifically: between (...) protocells and between biological living cells and protocells. It discusses how concepts such as control, cognition, communication can be used to characterize these interactions from a theoretical point of view, which criteria of relevance and evaluation of synthetic models can be applied to these cases, and what are their limits. (shrink)

Lam and Esfeld have argued that, within Bohmian mechanics, the wave function can be interpreted as a physical structure instantiated by the fundamental particles posited by the theory. Further, to characterize the nature of this structure, they appeal to the framework of Ontic Structural Realism, thereby proposing a structuralist interpretation of Bohmian mechanics. However, I shall point out that OSR denotes a family of distinct views, each of which maintains a different account about the relation between structures and objects, and (...) entails a different kind of ontology. Thus, in this paper I will show how to articulate the structuralist approach to Bohmian Mechanics accordingly to the different standard versions of OSR, and I will evaluate these alternatives. Moreover, I will propose a novel and _sui generis_ kind of structuralist interpretation of Bohmian Mechanics, based on the framework of metaphysical coherentism. (shrink)

The folk Psychology frames propositional attitudes as fundamental theoretical entities for the construction of a model designed to predict the behavior of a subject. A trivial, such as grasping a pen and writing reveals - something complex - about the behavior. When I take a pen and start writing I do, trivially, because I believe that a certain object in front of me is a pen and who performs a specific function that is, in fact, that of writing. When I (...) believe that the object that stands before me is a pen, I am in relation to "believe" with the propositional content: that in front of me is a pen. Philosophers of the proposition, from Frege onwards, have dedicated their studies to the analysis of what kinds of entities are the propositional attitudes. Jerry Fodor says that now, the proper prediction of the psychology of common sense, can not be questioned and that the propositional attitudes represent the most effective way to describe our behavior. What Fodor says, however, is that propositional attitudes function, but not how they work. Most philosophers interested in the issue, we are dedicated to the search for a theory that can account consistently both a semantics for propositional attitudes, both of these entities that seem to cause the behavior of a rational subject. There are two main paradigms in the theory of the proposition that contributed to the discussion of the propositional attitudes. One is the one that begins with Gottlob Frege, the other with Bertrand Russell. Defenders of Frege argue that the paradigm scrub objects and properties can not be constituents of the propositional content which have a purely conceptual. In other words, the philosophers belonging to the paradigm of Frege, but not all, mean that you can test in a rigorous way the truth conditions of propositional attitudes. Who defends the russellian’s paradigm argues that the propositional content are made by the objects and properties on which propositional attitudes relate. The purpose of this article is not to rebuild - in detail - both paradigms, nor to reconstruct one but, in a sense, my work will be a completely partial objective is to demonstrate how the paradigm is more profitable russell not only to make a coherent semantic theory for propositional attitudes2 but also to predict the behavior of a rational subject thing, completely innovative, given the repeated objections in contemporary literature3. At the end of this paper will be drafted a proposal to build a consistent model to predict the behavior,of a rational agent, based on a referential theory of propositional attitudes. (shrink)

Sfruttando alcune considerazioni, presenti in Richard (1997), riguardo questioni pragmatiche e psicologiche connesse alla semantica russelliana per i verbi psicologici si propone un modello teorico in cui, attraverso l’introduzione di alcuni enunciati strategici, ad es. “Lois non realizza che Superman è Clark Kent”, alcuni problemi connessi al diverso comportamento di Lois con gli individui Superman e Clark Kent, sembrerebbero risolti fornendoci corrette predizioni riguardo il comportamento di un agente razionale. Scopo di questo lavoro è estendere il modello ad alcuni casi (...) riguardanti l’etica delle credenze e mostrare, attraverso un caso paradigmatico nella letteratura specialistica, alcune potenziali conferme empiriche del modello stesso. (shrink)